This histologic section reveals urate deposits in the spinal canal that are impinging on the spinal cord. The animal presented with posterior paresis and tremors. Visceral and articular manifestations of gout are common in geckos, but are also seen in other reptiles. Gout is one differential for spinal cord lesions or "proliferative" lesions of the vertebrae. Other important differentials are trauma, bacterial osteomyelitis, degenerative joint disease, and neoplasia. Photo courtesy Northwest ZooPath.